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Welcome to
OAB
Academy

OAB Academy is a one-of-a-kind video library providing multidisciplinary perspectives on overactive bladder (OAB) care. Join us in uncovering valuable insights in the diagnosis.

Peer Perspectives

Urology Times National Broadcast

Patient Stories

Peer Perspectives

Treating OAB takes a team. Discover insights from our multidisciplinary OAB professionals, including urologists, nurse practitioners, and a pharmacist.

Carolyn Stahlhut, CRNP: A Treatment Option for OAB

Bilal Chughtai, MD: Recognizing OAB in Patients with BPH (benign prostatic hyperplasia)

Hany Mohamed, PharmD: The Pharmacist Perspective

Matt T. Rosenberg, MD: What is OAB?

Howard B. Goldman, MD FACS: Treating OAB Patients

Fast Facts

Quick! Stay informed on the impact of OAB, available treatment options, and the value of shared decision‐making when it comes to treating this chronic condition.

Fast Facts: Overcoming Barriers to Treatment

Fast Facts: The Value of Shared Decision‐Making

Fast Facts: Medication Types

Fast Facts: What is OAB?

Urology Times National Broadcast

Discover the impact of GEMTESA as an effective therapy for OAB in men being treated for BPH, presented by David Staskin, MD, and Kevin McVary, MD, FACS, as well as a real GEMTESA patient.

The Impact of OAB in Men with BPH

Efficacy and Safety From the Phase 3 COURAGE Trial

Patient Experience with GEMTESA

Q&A

Patient Stories

Patients are raising their voices and becoming Go-Getters. Are you ready to listen? Hear real patients taking GEMTESA recount their experience with diagnosis, coping with OAB symptoms, and starting GEMTESA.

Get Going with Holly and Join the GEMTESA Go-Getters

Diane Doesn’t Let Age or OAB Define Her

Lois Told OAB to Stay in its Lane

Getting Candid with the Go-Getters

Bruce Goes the Distance Despite OAB

OAB Academy Sponsored by Sumitomo Pharma

For additional content on OAB care, please visit our YouTube page.

See how GEMTESA could help your patients

GEMTESA® is a beta-3 adrenergic agonist indicated for the treatment of:

overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults.
overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adult males on pharmacological therapy for benign prostatic hyperplasia (BPH).

IMPORTANT SAFETY INFORMATION

CONTRAINDICATIONS

GEMTESA is contraindicated in patients with known hypersensitivity to vibegron or any components of GEMTESA. Hypersensitivity reactions, such as angioedema, have occurred.

WARNINGS AND PRECAUTIONS

Urinary Retention

Urinary retention has been reported in patients taking GEMTESA. The risk of urinary retention may be increased in patients with bladder outlet obstruction and also in patients taking muscarinic antagonist medications for the treatment of OAB. Monitor patients for signs and symptoms of urinary retention, particularly in patients with bladder outlet obstruction and patients taking muscarinic antagonist medications for the treatment of OAB. Discontinue GEMTESA in patients who develop urinary retention.

Angioedema

Angioedema of the face and/or larynx has been reported with GEMTESA. Angioedema has been reported to occur hours after the first dose or after multiple doses. Angioedema, associated with upper airway swelling, may be life-threatening. If involvement of the tongue, hypopharynx, or larynx occurs, immediately discontinue GEMTESA and provide appropriate therapy and/or measures necessary to ensure a patent airway.

ADVERSE REACTIONS

Most common adverse reactions (≥2%) reported with GEMTESA were headache, urinary tract infection, nasopharyngitis, diarrhea, nausea, and upper respiratory tract infection.

INDICATIONS AND USAGE

GEMTESA® is a beta-3 adrenergic agonist indicated for the treatment of:

overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults.
overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adult males on pharmacological therapy for benign prostatic hyperplasia (BPH).

IMPORTANT SAFETY INFORMATION

CONTRAINDICATIONS

GEMTESA is contraindicated in patients with known hypersensitivity to vibegron or any components of GEMTESA. Hypersensitivity reactions, such as angioedema, have occurred.

WARNINGS AND PRECAUTIONS

Urinary Retention

Urinary retention has been reported in patients taking GEMTESA. The risk of urinary retention may be increased in patients with bladder outlet obstruction and also in patients taking muscarinic antagonist medications for the treatment of OAB. Monitor patients for signs and symptoms of urinary retention, particularly in patients with bladder outlet obstruction or patients taking muscarinic antagonist medications for the treatment of OAB. Discontinue GEMTESA in patients who develop urinary retention.

Angioedema

Angioedema of the face and/or larynx has been reported with GEMTESA. Angioedema has been reported to occur hours after the first dose or after multiple doses. Angioedema, associated with upper airway swelling, may be life-threatening. If involvement of the tongue, hypopharynx, or larynx occurs, immediately discontinue GEMTESA and provide appropriate therapy and/or measures necessary to ensure a patent airway.

ADVERSE REACTIONS

Most common adverse reactions (≥2%) reported with GEMTESA were headache, urinary tract infection, nasopharyngitis, diarrhea, nausea, and upper respiratory tract infection.

Please see full Prescribing Information.

References:

Approved Drug Products With Therapeutic Equivalence Evaluations. 44th Edition. US Dept of Health and Human Services; 2024.
Yang CF, Huang CY, Wang SY, Chang SR. Prevalence of and associated factors for overactive bladder subtypes in middle-aged women: a cross-sectional study. Medicina (Kaunas). 2022;58(3):383. doi:10.3390/medicina58030383
Data on file. Sumitomo Pharma America, Inc.
Filipetto FA, Fulda KG, Holthusen AE, McKeithen TM, McFadden P. The patient perspective on overactive bladder: a mixed-methods needs assessment. BMC Fam Pract. 2014;15:96. doi:10.1186/1471-229-15-96

STUDIED IN MORE THAN 1500 PATIENTS WITH OAB^1,2

12-week double-blind treatment period²

12 week double blind treatment period, Diagram

12 week double blind treatment period, Diagram

50.6% OF PATIENTS ENROLLED HAD HYPERTENSION AT BASELINE³

A 12-week, Phase 3, randomized, double-blind, placebo- and active-controlled multicenter study to evaluate the safety and efficacy of GEMTESA in 1500+ patients with symptoms of OAB.^1,2

12-week patient demographics^1-3

60

Years Old
Mean Age

FEMALE

85%

FEMALE

MALE

15%

MALE

Treatment naïve or had prior ACh or β₃-agonist use in 12 months before study

77% OAB WET*

23% OAB DRY*

Symptoms of OAB ≥3 months with average ≥8 micturitions/day and ≥1 UUI/day, or average ≥8 micturitions/day and average ≥3 urgency episodes/day^2†

* OAB wet=average of ≥1 urge urinary incontinence episode per day; OAB dry=average of ≥3 urgency episodes and average of <1 urge urinary incontinence episode per day.²

^† UUI was defined as leakage of urine of any amount because the patient felt an urge or need to urinate immediately.¹

GEMTESA met efficacy endpoints^1,2

12-week study efficacy endpoints

Co-primary endpoints

CFB in average daily number of micturitions and urge urinary incontinence episodes at Week 12

Key secondary endpoints

CFB in average daily number of urgency episodes at Week 12
Percent of OAB-wet patients at Week 12 with ≥75% reduction in total number of urge urinary incontinence episodes in 24 hours*
Percent of all OAB patients at Week 12 with 50% reduction in total number of urgency episodes per 24 hours*

Efficacy analyses were performed using the FAS, except for incontinence episode endpoints, which used the FAS-I.²

* Data were based on unadjusted values for a supportive outcome measure that was a prescribed secondary endpoint in the pivotal EMPOWUR trial.²
ACh=anticholinergic; CFB=change from baseline; FAS=full analysis set; FAS-I=full analysis set for incontinence; OAB=overactive bladder; UUI=urge urinary incontinence.

References:

GEMTESA. Prescribing Information. Marlborough, MA; Sumitomo Pharma America; 2025.
Staskin D, Frankel J, Varano S, Shortino D, Jankowich R, Mudd PN Jr. International phase III, randomized, double-blind, placebo and active controlled study to evaluate the safety and efficacy of vibegron in patients with symptoms of overactive bladder: EMPOWUR. J Urol. 2020;204(2):316-324. doi:10.1097/JU.0000000000000807
Data on file. Sumitomo Pharma America, Inc.